Protein name:
Serine/arginine repetitive matrix protein 4 ;
Alternative:
Neural-specific serine/arginine repetitive splicing factor of 100 kDa (Neural-specific SR-related protein of 100 kDa;nSR100) ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Splicing factor specifically required for neural cell differentiation. Acts in conjuction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MASLQQGEKQ | LFEKFWKGTF | KAVATPRPES | IIVASITARK | PMPRTEPQSS |
100:
LLLPDQDGPS | EKLGQHLAPE | ALGTNSWGRE | KACRELDPAR | AHSASQDRDP |
150:
TPPPSSRGKK | KKKKSTRKKR | RRSPSYSPSP | VKKKKKKSSK | KHKRHRSFSK |
200:
KRRHSSCSPK | SKRREEKRHK | KQSRSRKSHR | HRHHRCPSRS | QSSELRSPSC |
250:
ESRHRGRSPE | EGRKSRRTHS | RRCSKNHCKV | SPDARSSHLP | SQPLPRLGFL |
300:
SARGVITGSG | SAADLFSKSA | SPLAATRGRS | QEYDSGNDTS | SPPSTQTSSA |
350:
RSRGQEKGSP | GGDLSKSRDL | NCGNTSDSGN | SFTTSSPQNK | GAVLETVSPA |
400:
CRSRESRGFQ | SPCLQCAEVK | KSSLVPSTAR | SSPIKECSRS | SSYTSTRSSS |
450:
PSSRSPNPRA | SPRYTRSRST | SSEKRSYSRS | PSYSSKSGKR | SPPSRSSRSR |
500:
RSPSYSRYSP | SRERDLKYGE | KEPQPRERAR | RRRRSYSPMR | KRRRDSPSHL |
550:
EARRITSARK | RPIPYYRPSP | SSSSSLSSAS | SWYSSSSSSS | SSSSRSPSRS |
600:
YSRSRSPSRS | HSSRSQTRSR | TRTSRSSSSR | SLSLGSRSRS | RNRSLSYSSA |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Mouse Serine/arginine repetitive matrix protein 4
ELISA Kit for Mouse Serine/arginine repetitive matrix protein 4
CLIA Kit for Mouse Serine/arginine repetitive matrix protein 4
CLIA Kit for Mouse Serine/arginine repetitive matrix protein 4
Polyclonal Antibody for Mouse Serine/arginine repetitive matrix protein 4
Polyclonal Antibody for Mouse Serine/arginine repetitive matrix protein 4
Monoclonal Antibody for Mouse Serine/arginine repetitive matrix protein 4
Monoclonal Antibody for Mouse Serine/arginine repetitive matrix protein 4
Protein for Mouse Serine/arginine repetitive matrix protein 4
Protein for Mouse Serine/arginine repetitive matrix protein 4
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
C57BL/6J .
tissue :
Cerebellum .
tissue :
Eye .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
strain :
C57BL/6 .
strain :
FVB/N .
tissue :
Brain .
tissue :
Liver .
3.
"Regulation of vertebrate nervous system alternative splicing and development by an SR-related protein."
Calarco J.A.
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Superina S.
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O'Hanlon D.
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Gabut M.
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Raj B.
,
Pan Q.
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Skalska U.
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Clarke L.
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Gelinas D.
,
van der Kooy D.
,
Zhen M.
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Ciruna B.
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Blencowe B.J.
Cell138:898-910(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;RNA-BINDING;PHOSPHORYLATION